Search for: All
Publications by "Heuser, J" (NIH/Medline)
[may
include results
from others
with same
name]
NAME |
John Edward Heuser |
BORN |
August 29, 1942; Pittsburgh, Pennsylvania,
U.S.A. |
PERSONAL |
Married, with three children born '80, '82
and '85, plus one stepchild |
EDUCATION |
1964, B.A., cum laude, Harvard College
1969, M.D., magna cum laude, Harvard Medical
School
1970-1973, Graduate studies in Biophysics, University
College London |
PRESENT POSITION |
Professor
of Biophysics, Department of Cell Biology
and Physiology
Washington University School of Medicine
660 South Euclid Avenue, St.
Louis, Missouri 63110 |
EXPERIENCE |
1963-1967 |
Undergraduate apprentice in
J. David Robertson's Electron
Microscopy Lab, Harvard Medical
School and the McLean Hospital,
Belmont, MA |
1969-1974 |
USPHS Fellow and Moseley Travelling
Fellow of Harvard University,
as Postdoctoral trainee in the
Biophysics Unit of University
College, London, under Sir Bernard
Katz and Ricardo Miledi |
1970-1972 |
USPHS Military service in Laboratory
of Neuropathology and Neuroanatomical
Sciences, NINCDS, Bethesda,
MD with Dr. Thomas S. Reese |
1974-1980 |
Assistant, Associate, and then
Full Professor of Physiology,
Department of Physiology, University
of California, San Francisco,
CA |
1980- |
Professor of Biophysics, Department
of Cell Biology and Physiology,
Washington University School
of Medicine, St. Louis, MO 63110 |
|
AWARDS |
Borden
Award for outstanding research in medical
school, 1969
Moseley
Travelling Fellowship of Harvard University
1972-73
First
annual Bensley Memorial Lectureship,
American Association of Anatomists,
1979
Alden
Spencer Award, Columbia University, 1980
Alexander
Forbes Memorial Lectureship, Grass Foundation,
1981
Keith
R. Porter Memorial Lectureship, American
Society for Cell Biology, 1985
Carl
Zeiss Lectureship, European Society for
Cell Biology, 1995
Kuffler
Memorial Lectureship, Stanford University,
1999
Christiana
Smith Lectureship, Mt.Hoyoke & Smith
Colleges, 2001
A.R.
Martin Lectureship, University of Colorado,
2004
Fellow,
American American Academy of Arts and
Sciences, 2005
Fellow,
American Association for the Advancement of
Science, 2007 |
PROFESSIONAL ACTIVITIES |
Associate
Editor of the Journal of Cell Biology
(past)
Associate
Editor of the Journal of Neurocytology
(curr)
Service
to editorial boards of: Journal
of Neurophysiology, Brain Research,
Journal of Comparative Neurology,
Journal of Neuroscience Methods, Gastroenterology,
Cell, Anatomical Record, Journal of
Molecular Biology, etc.
Ad
Hoc reviewer for NINCDS, NCRR, and National
Science Foundation |
TEACHING ACTIVITIES |
1980-1990 |
Lecturer (with U.W.
Goodenough) in Washington University
Medical School courses in Cell Biology
and Neurobiology |
1980-1995 |
Lecturer in Washington University
Medical School courses in Cell Biology
and Neurobiology |
1974-1980 |
Lecturer in UCSF graduate and medical
school courses: Cell Biology and
Neurobiology |
1974-1995 |
Director of graduate course: Neuroanatomical
Methods |
1975-1998 |
Instructor, Summer Neurobiology
course, Marine Biological Laboratory,
Woods Hole, MA |
|
CURRENT RESEARCH INTERESTS |
1. Freeze-etch
electron microscopy as applied to cell
and molecular biology
2. The
structural basis of neuronal synaptic
transmission |
Linked information
supplied by PubMed. We are not responsible for its
content or accuracy.
Full-text access policies vary by journal/publisher.
- Heuser, J. E. and C. F. Doggenweiler (1966). The
fine structural organization of nerve fibers, sheaths, and glial cells in
the prawn, Palaemonetes vulgaris. J Cell Biol 30: 381-403.
- Doggenweiler, C. F. and J. E. Heuser (1967). Ultrastructure
of the prawn nerve sheaths. Role of fixative and osmotic pressure in vesiculation
of thin cytoplasmic laminae. J Cell Biol 34: 407-20.
- Heuser, J. and R. Miledi (1970). Autoradiography
of labelled amino acids injected iontophoretically into the giant squid
synapse. J Physiol 208: 55P-57P.
- Heuser, J., B. Katz and R. Miledi (1971). Structural
and functional changes of frog neuromuscular junctions in high calcium solutions.
Proc R Soc Lond B Biol Sci 178: 407-15.
- Heuser, J. and R. Miledi (1971). Effects
of lanthanum ions on function and structure of frog neuromuscular junctions.
Proc R Soc Lond B Biol Sci 179: 247-60.
- Heuser, J. and A. M. Lennon (1973). Morphological
evidence for exocytosis of acetylcholine during formation of synaptosomes
from Torpedo electric organ. J Physiol 233: 39P-41P.
- Heuser, J. E. and T. S. Reese (1973). Evidence
for recycling of synaptic vesicle membrane during transmitter release at
the frog neuromuscular junction. J Cell Biol 57: 315-44.
- Jablecki, C. K., J. E. Heuser and S. Kaufman
(1973). Autoradiographic
localization of new RNA synthesis in hypertrophying skeletal muscle. J
Cell Biol 57: 743-59.
- Heuser, J. E. (1974). Proceedings: A possible
origin of the 'giant' spontaneous potentials that occur after prolonged transmitter
release at fr sog neuromuscular junctions. J Physiol 239: 106P-108P.
- Heuser, J. E. and T. S. Reese (1974). Morphology
of synaptic vesicle discharge and reformation at the frog neuromuscular junction
in: M. V. L. Bennett (eds.), Synaptic Transmission and Neuronal Interaction
(pp. 59-78). New York: Raven Press.
- Heuser, J. E., T. S. Reese and D. M. Landis
(1974). Functional
changes in frog neuromuscular junctions studied with freeze-fracture.
J Neurocytol 3: 109-31.
- Heuser, J. E. (1976). Morphology of synaptic
vesicle discharge and reformation at the frog neuromuscular junction in: S.
Thesleff (eds.), The Motor Innervation of Muscle (pp. 51-115). London: Academic
Press.
- Heuser, J. E. (1976). Ultrafast freezing
to capture the structural changes that underlie neuromuscular transmission
in: L. P. Rowland (eds.), Exploratory Concepts in Muscular Dystrophy (pp.
215-239). Amsterdam: Excerpta Medica.
- Heuser, J. E., T. S. Reese and D. M. Landis
(1976). Preservation
of synaptic structure by rapid freezing. Cold Spring Harb Symp Quant Biol
40: 17-24.
- Heuser, J. E. (1977). Synaptic vesicle exocytosis
revealed in quick-frozen frog neuromuscular junctions treated with 4-ampyrodine
and given a single electrical shock. pp. 215-239 in: Society for Neuroscience
Symposia, Vol II: Approaches to the Cell Biology of Neurons, eds: W.M.Cowan
and J.A.Ferrandelli. Soc.Neurosci, Bethesda, MD.
- Heuser, J. E. and R. Llinas (1977). Depolarization-release
coupling: report of a neurosciences research program workshop in: (eds.),
NRP Bulletin (pp. 603-622).
- Heuser, J. E. and T. S. Reese (1977). The
structure of the synapse in: Handbook of the Nervous System (pp. 261-294).
- Strong, P. N., J. E. Heuser and R. B. Kelly
(1977). Selective
enzymatic hydrolysis of nerve terminal phospholipids by beta-bungarotoxin:
biochemical and morphological studies. Prog Clin Biol Res 15: 227-49.
- Franzini-Armstrong, C., J. E. Heuser, T.
S. Reese, A. P. Somlyo and A. V. Somlyo (1978). T-tubule
swelling in hypertonic solutions: a freeze substitution study. J Physiol
283: 133-40.
- Heuser, J. E. (1978). Quick-freezing evidence
in favor of the vesicular hypothesis. Trends in Neurosciences: 80-82.
- Heuser, J. E. (1978). Synaptic vesicle exocytosis
and recycling during transmitter discharge from the neuromuscular junction
in: S. C. Silverstein (eds.), Life Science Research Report (pp. 445-464).
Berlin: Dahlem Konferenzen.
- Basbaum, C. B. and J. E. Heuser (1979). Morphological
studies of stimulated adrenergic axon varicosities in the mouse vas deferens.
J Cell Biol 80: 310-25.
- Chandler, D. E. and J. Heuser (1979). Membrane
fusion during secretion: cortical granule exocytosis in sex urchin eggs
as studied by quick-freezing and freeze-fracture. J Cell Biol 83: 91-108.
- Heuser, J. E. and T. S. Reese (1979). Synaptic
vesicle exocytosis captured by quick-freezing in: (eds.), Fourth N.R.P. Intensive
Study Program (pp. 573-600). Cambridge: MIT Press.
- Heuser, J. E. and T. S. Reese (1979). Changes
in structure of the presynaptic membrane during transmitter secretion in:
M. Otsuka and Z. Hall (eds.), Neurobiology of Synaptic Transmission (pp. 3-11).
Toronto: Wiley & Sons.
- Heuser, J. E., T. S. Reese, M. J. Dennis,
Y. Jan, L. Jan and L. Evans (1979). Synaptic
vesicle exocytosis captured by quick freezing and correlated with quantal
transmitter release. J Cell Biol 81: 275-300.
- Heuser, J. E. and S. R. Salpeter (1979). Organization
of acetylcholine receptors in quick-frozen, deep-etched, and rotary-replicated
Torpedo postsynaptic membrane. J Cell Biol 82: 150-73.
- Heuser, J. E. and S. R. Salpeter (1979).
Ultrastructure of the cholinergic synapse in: (eds.), The Cholinergic Synapse
(pp. 478-480).
- Shotton, D. M., J. E. Heuser, B. F. Reese
and T. S. Reese (1979). Postsynaptic
membrane folds of the frog neuromuscular junction visualized by scanning electron
microscopy. Neuroscience 4: 427-35.
- Stevens, C. F. (1979). The neuron [micrographs
provided by J. Heuser]. Sci Am 241: 54-65.
- Chandler, D. E. and J. Heuser (1980). The
vitelline layer of the sea urchin egg and its modification during fertilization.
A freeze-fracture study using quick-freezing and deep-etching. J Cell
Biol 84: 618-32.
- Chandler, D. E. and J. E. Heuser (1980). Arrest
of membrane fusion events in mast cells by quick-freezing. J Cell Biol
86: 666-74.
- Heuser, J. (1980). Three-dimensional
visualization of coated vesicle formation in fibroblasts. J Cell Biol
84: 560-83.
- Heuser, J. E. (1980). A budding field in
cell biology (Review). Cell 22: 634-636.
- Heuser, J. E. (1980). 3-D visualization
of membrane and cytoplasmic specializations at the frog neuromuscular junction
in: Taxi (eds.), INSERM Symposium (pp.: Elsevier/North Holland Biomedical
Press.
- Heuser, J. E. (1980). Quick-freeze, deep-etch
method of preparing samples for 3-D electron microscopy. Trends in Biochemical
Sciences 6: 64-68.
- Heuser, J. E. and M. W. Kirschner (1980). Filament
organization revealed in platinum replicas of freeze-dried cytoskeletons.
J Cell Biol 86: 212-34.
- Klymkowsky, M. W., J. E. Heuser and R. M.
Stroud (1980). Protease
effects on the structure of acetylcholine receptor membranes from Torpedo
californica. J Cell Biol 85: 823-38.
- Chandler, D. E. and J. Heuser (1981). Postfertilization
growth of microvilli in the sea urchin egg: new views from eggs that have
been quick-frozen, freeze-fractured, and deeply etched. Dev Biol 82:
393-400.
- Friend, D. S. and J. E. Heuser (1981). Orderly
particle arrays on the mitochondrial outer membrane in rapidly-frozen sperm.
Anat Rec 199: 159-75.
- Heuser, J. (1981). Preparing
biological samples for stereomicroscopy by the quick-freeze, deep-etch,
rotary-replication technique. Methods Cell Biol 22: 97-122.
- Heuser, J. E. and T. S. Reese (1981). Structural
changes after transmitter release at the frog neuromuscular junction.
J Cell Biol 88: 564-80.
- Hirokawa, N. and J. E. Heuser (1981). Structural
evidence that botulinum toxin blocks neuromuscular transmission by impairing
the calcium influx that normally accompanies nerve depolarization. J
Cell Biol 88: 160-71.
- Hirokawa, N. and J. E. Heuser (1981). Quick-freeze,
deep-etch visualization of the cytoskeleton beneath surface differentiations
of intestinal epithelial cells. J Cell Biol 91: 399-409.
- Aggeler, J. and Z. Werb (1982). Initial events
during phagocytosis by macrophages viewed from outside and inside the cell:
membrane-particle interactions and clathrin. J Cell Biol 94: 613-23. [directed,
illustrated, and supported by J.E. Heuser]
- Goodenough, U. W. and J. E. Heuser (1982). Substructure
of the outer dynein arm. J Cell Biol 95: 798-815.
- Hirokawa, N. and J. Heuser (1982). The
inside and outside of gap-junction membranes visualized by deep etching.
Cell 30: 395-406.
- Hirokawa, N. and J. E. Heuser (1982). Internal
and external differentiations of the postsynaptic membrane at the neuromuscular
junction. J Neurocytol 11: 487-510.
- Hirokawa, N. and J. E. Heuser (1982). Cross-linker
system between neurofilaments, microtubules, and membranous organelles in
frog axons revealed by the quick-freeze, deep-etching method. J Cell
Biol 94: 129-42.
- Hirokawa, N., L. G. Tilney, K. Fujiwara and J.
E. Heuser (1982). Organization
of actin, myosin, and intermediate filaments in the brush border of intestinal
epithelial cells. J Cell Biol 94: 425-43.
- Roof, D. J. and J. E. Heuser (1982). Surfaces
of rod photoreceptor disk membranes: integral membrane components. J
Cell Biol 95: 487-500.
- Roof, D. J., J. I. Korenbrot and J. E. Heuser (1982). Surfaces
of rod photoreceptor disk membranes: light-activated enzymes. J Cell
Biol 95: 501-9.
- Schaeffer, S. F., E. Raviola and J. E. Heuser (1982). Membrane
specializations in the outer plexiform layer of the turtle retina. J
Comp Neurol 204: 253-67.
- Adair, W. S., C. Hwang and U. W. Goodenough (1983).
Identification and visualization of the sexual agglutinin from the mating-type
plus flagellar membrane of Chlamydomonas. Cell 33: 183-93. [Figures by J.E. Heuser]
- Cooper, J. B., W. S. Adair, R. P. Mecham, J. E. Heuser and
U. W. Goodenough (1983). Chlamydomonas agglutinin is a hydroxyproline-rich
glycoprotein. Proc Natl Acad Sci USA 80: 5898-5901.
- Harding, C., J. Heuser and P. Stahl (1983). Receptor-mediated
endocytosis of transferrin and recycling of the transferrin receptor in
rat reticulocytes. J Cell Biol 97: 329-39.
- Harding, C. and P. Stahl (1983). Transferrin recycling
in reticulocytes: pH and iron are important determinants of ligand binding
and processing. Biochem Biophys Res Commun 113: 650-8. [directed & supported
by J.E. Heuser]
- Heuser, J. E. (1983). Structure
of the myosin crossbridge lattice in insect flight muscle. J Mol Biol
169: 123-54.
- Heuser, J. E. (1983). Procedure
for freeze-drying molecules adsorbed to mica flakes. J Mol Biol 169:
155-95.
- Heuser, J. E. and R. Cooke (1983). Actin-myosin
interactions visualized by the quick-freeze, deep-etch replica technique.
J Mol Biol 169: 97-122.
- Ip, W. and J. Heuser (1983). Direct
visualization of the myosin crossbridge helices on relaxed rabbit psoas
thick filaments. J Mol Biol 171: 105-9.
- Monk, B. C., W. S. Adair, R. A. Cohen and U. W.
Goodenough (1983). Topography of Chlamydomonas: fine structure and polypeptide
components of the gametic flagellar membrane surface and the cell wall. Planta
158: 517-533. [Micrographs provided by J. Heuser]
- Goodenough, U. and J. Heuser (1984). Structural
comparison of purified dynein proteins with in situ dynein arms. J Mol
Biol 180: 1083-118.
- Goodenough, W., W. S. Adair, P. Colllin-Osdoby
and J. E. Heuser (1984). Chlamydomonas cells in contact in: E. Gall
and G. Edelman (eds.), Cells In Contact New York: John Wiley.
- Harding, C., J. Heuser and P. Stahl (1984). Endocytosis
and intracellular processing of transferrin and colloidal gold-transferrin
in rat reticulocytes: demonstration of a pathway for receptor shedding.
Eur J Cell Biol 35: 256-63.
- Ip, W., D. B. Murphy and J. E. Heuser (1984). Arrest
of pigment granule motion in erythrophores by quick-freezing. J Ultrastruct
Res 86: 162-75.
- Miller, T. M. and J. E. Heuser (1984). Endocytosis
of synaptic vesicle membrane at the frog neuromuscular junction. J Cell
Biol 98: 685-98.
- Souto-Padron, T., W. de Souza and J. E. Heuser (1984). Quick-freeze,
deep-etch rotary replication of Trypanosoma cruzi and Herpetomonas megaseliae.
J Cell Sci 69: 167-78.
- Goodenough, U. W., W. S. Adair, P. Collin-Osdoby
and J. E. Heuser (1985). Structure
of the Chlamydomonas agglutinin and related flagellar surface proteins in
vitro and in situ. J Cell Biol 101: 924-41.
- Goodenough, U. W., W. S. Adair, P. Collin-Osdoby
and J. E. Heuser (1985). Chapter 6: Chlamydomonas Cells in Contact
in: G. Edelman and J.-P. Theiry (eds.), The Cell In Contact: Adhesions and
Junctions as Morphogenetic Determinants (pp. 111-135). San Diego: Neurosciences
Research Foundation, Inc.
- Goodenough, U. W. and J. E. Heuser (1985). Substructure
of inner dynein arms, radial spokes, and the central pair/projection complex
of cilia and flagella. J Cell Biol 100: 2008-18.
- Goodenough, U. W. and J. E. Heuser (1985). Outer
and inner dynein arms of cilia and flagella. Cell 41: 341-2.
- Goodenough, U. W. and J. E. Heuser (1985). The
Chlamydomonas cell wall and its constituent glycoproteins analyzed by the
quick-freeze, deep-etch technique. J Cell Biol 101: 1550-68.
- Heuser, J. and T. Kirchhausen (1985). Deep-etch
views of clathrin assemblies. J Ultrastruct Res 92: 1-27.
- Ip, W., J. E. Heuser, Y. Y. Pang, M. K.
Hartzer and R. M. Robson (1985). Subunit
structure of desmin and vimentin protofilaments and how they assemble into
intermediate filaments. Ann N Y Acad Sci 455: 185-99.
- Sale, W. S., U. W. Goodenough and J. E. Heuser (1985). The
substructure of isolated and in situ outer dynein arms of sea urchin sperm
flagella. J Cell Biol 101: 1400-12.
- Goodenough, U. W., B. Gebhart, R. P. Mecham and
J. E. Heuser (1986). Crystals
of the Chlamydomonas reinhardtii cell wall: polymerization, depolymerization,
and purification of glycoprotein monomers. J Cell Biol 103: 405-17.
- Heuser, J. E. (1986). Different
structural states of a microtubule cross-linking molecule, captured by quick-freezing
motile axostyles in protozoa. J Cell Biol 103: 2209-27.
- Kirchhausen, T., S. C. Harrison and J. Heuser (1986). Configuration
of clathrin trimers: evidence from electron microscopy. J Ultrastruct
Mol Struct Res 94: 199-208.
- Adair, W. S., S. A. Steinmetz, D. M. Mattson, U.
W. Goodenough and J. E. Heuser (1987). Nucleated
assembly of Chlamydomonas and Volvox cell walls. J Cell Biol 105: 2373-82.
- Conzelman, K. A. and M. S. Mooseker (1987). The 110-kD
protein-calmodulin complex of the intestinal microvillus is an actin-activated
MgATPase. J Cell Biol 105: 313-24.
- Goodenough, U. W., B. Gebhart, V. Mermall, D. R.
Mitchell and J. E. Heuser (1987). High-pressure
liquid chromatography fractionation of Chlamydomonas dynein extracts and characterization
of inner-arm dynein subunits. J Mol Biol 194: 481-94.
- Heuser, J. E. (1987). Crossbridges
in insect flight muscles of the blowfly (Sarcophaga bullata). J Muscle
Res Cell Motil 8: 303-21.
- Heuser, J. E., J. H. Keen, L. M. Amende,
R. E. Lippoldt and K. Prasad (1987). Deep-etch
visualization of 27S clathrin: a tetrahedral tetramer. J Cell Biol 105:
1999-2009.
- Peterson, J. B., J. E. Heuser and D. L.
Nelson (1987). Dissociation
and reassociation of trichocyst proteins: biochemical and ultrastructural
studies. J Cell Sci 87 ( Pt 1): 3-25.
- Collier, N. C., J. Heuser, M. A. Levy and
M. J. Schlesinger (1988). Ultrastructural
and biochemical analysis of the stress granule in chicken embryo fibroblasts.
J Cell Biol 106: 1131-9.
- Goodenough, U. W. and J. E. Heuser (1988).
Molecular reorganization of cell wall crystals from Chlamydomonas reinhardtii
and Volvox carteri. Journal of Cell Science 90: 717-733.
- Goodenough, U. W. and J. E. Heuser (1988).
Molecular organization of the cell wall and cell-wall crystals from Chlamydomonas
eugamatos. J Cell Sci 90: 735-750.
- Heuser, J. E. and J. Keen (1988). Deep-etch
visualization of proteins involved in clathrin assembly. J Cell Biol
107: 877-86.
- Solans, C., J. G. Dominguez, J. L. Parra, J. E. Heuser and
S. E. Friberg (1988). Gelled emulsions with a high water content. Colloid
and Polymer Science 266: 570-574.
- Coleman, T. R., D. J. Fishkind, M. S. Mooseker
and J. S. Morrow (1989). Functional diversity among spectrin isoforms. Cell
Motility & the Cytoskeleton 12: 225-47. [Micrographs provided by J. Heuser]
- Friberg, S., Y. Liang, J. E. Heuser and
W. Benton (1989). Surfactant association structures in the system water, orbitol,
sodium dodecyl sulfate and hexanol. Journal of Colloid and Interface Science
132: 810-818.
- Goodenough, U. W. and J. E. Heuser (1989).
Structure of the soluble and in situ ciliary dyneins visualized by quick-freeze,
deep-etch electron microscopy in: F. Warner (eds.), Cell Movement, Vol 1:
Te Dynein ATPases (pp. 121-140). New York: A.R. Liss Inc.
- Goodenough, U. W. and J. E. Heuser (1989).
Recognition proteins of Chlamydomonas reinhardtii (chlorophyceae) in: A. W.
Coleman, L. J. Gooff and J. R. Stein-Taylor (eds.), Algae as Experimental
Systems (pp. 171-185). New York: Alan R. Liss Inc.
- Heuser, J. (1989). Effects
of cytoplasmic acidification on clathrin lattice morphology. J Cell
Biol 108: 401-11.
- Heuser, J. (1989). Changes
in lysosome shape and distribution correlated with changes in cytoplasmic
pH. J Cell Biol 108: 855-64.
- Heuser, J. (1989). Protocol
for 3-D visualization of molecules on mica via the quick-freeze, deep-etch
technique. J Electron Microsc Tech 13: 244-63.
- Heuser, J. (1989). The
role of coated vesicles in recycling of synaptic vesicle membrane. Cell
Biology International Reports 13: 1063-76.
- Heuser, J. and J. Griffith (1989). Visualization
of RecA protein and its complexes with DNA by quick-freeze/deep-etch electron
microscopy. J Mol Biol 210: 473-84.
- Heuser, J. and C. J. Steer (1989). Trimeric
binding of the 70-kD uncoating ATPase to the vertices of clathrin triskelia:
a candidate intermediate in the vesicle uncoating reaction. J Cell Biol
109: 1457-66.
- Heuser, J. E. (1989). Development
of the quick-freeze, deep-etch, rotary-replication technique of sample preparation
for 3-D electron microscopy. Prog Clin Biol Res 295: 71-83.
- Heuser, J. E. (1989). Mechanisms
behind the organization of membranous organelles in cells. Curr Opin
Cell Biol 1: 98-102.
- Heuser, J. E. (1989). Review
of electron microscopic evidence favouring vesicle exocytosis as the structural
basis for quantal release during synaptic transmission. Q J Exp Physiol
74: 1051-69.
- Heuser, J. E. and R. G. Anderson (1989). Hypertonic
media inhibit receptor-mediated endocytosis by blocking clathrin-coated
pit formation. J Cell Biol 108: 389-400.
- Hollenbeck, P. (1989). Cell motility. Dissecting
a molecular motor [micrographs provided by J. Heuser]. Nature 338:
294-5.
- Kim, J. I., J. Heuser and M. M. Cox (1989). Enhanced
recA protein binding to Z DNA represents a kinetic perturbation of a general
duplex DNA binding pathway. J Biol Chem 264: 21848-56.
- Mooseker, M. S., K. A. Conzelman, T. R. Coleman,
J. E. Heuser and M. P. Sheetz (1989). Characterization
of intestinal microvillar membrane disks: detergent-resistant membrane sheets
enriched in associated brush border myosin I (110K-calmodulin). J Cell
Biol 109: 1153-61.
- Scholey, J. M., J. Heuser, J. T. Yang and
L. S. Goldstein (1989). Identification
of globular mechanochemical heads of kinesin. Nature 338: 355-7.
- Mecham, R. P. and J. Heuser (1990). Three-dimensional
organization of extracellular matrix in elastic cartilage as viewed by quick
freeze, deep etch electron microscopy. Connect Tissue Res 24: 83-93.
- Kedersha, N. L., J. E. Heuser, D. C. Chugani
and L. H. Rome (1991). Vaults.
III. Vault ribonucleoprotein particles open into flower-like structures with
octagonal symmetry. J Cell Biol 112: 225-35.
- Mecham, R. P. and J. E. Heuser (1991). The
Elastic Fiber in: E. Hay (eds.), Cell Biology of the Extracellular Matrix
(pp. New York: Plenum Press.
- Sampson, L. L., J. Heuser and E. J. Brown
(1991). Cytokine
regulation of complement receptor-mediated ingestion by mouse peritoneal macrophages.
M-CSF and IL-4 activate phagocytosis by a common mechanism requiring autostimulation
by IFN-beta. J Immunol 146: 1005-13.
- Steer, C. J. and J. E. Heuser (1991). Clathrin
and coated vesicles: critical determinants of intracellular trafficking in:
C. J. Steer and J. A. Hanover (eds.), Intracellular Trafficking of Proteins
(pp. 47-102). Cambridge: Cambridge University Press.
- Van Etten, J. L., L. C. Lane and R. H. Meints (1991). Viruses
and viruslike particles of eukaryotic algae. Microbiological Reviews
55: 586-620. [All micrographs provided by J.E. Heuser]
- Baumrind, N. L., D. Parkinson, D. B. Wayne, J.
E. Heuser and A. L. Pearlman (1992). EMA:
a developmentally regulated cell-surface glycoprotein of CNS neurons that
is concentrated at the leading edge of growth cones. Dev Dyn 194: 311-25.
- Castellino, F., J. Heuser, S. Marchetti,
B. Bruno and A. Luini (1992). Glucocorticoid
stabilization of actin filaments: a possible mechanism for inhibition of corticotropin
release. Proc Natl Acad Sci U S A 89: 3775-9.
- Goldberg, A. L. and K. L. Rock (1992). Proteolysis,
proteasomes and antigen presentation [micrographs provided by J. Heuser].
Nature 357: 375-9.
- Kuehn, M. J., J. Heuser, S. Normark and
S. J. Hultgren (1992). P
pili in uropathogenic E. coli are composite fibres with distinct fibrillar
adhesive tips. Nature 356: 252-5.
- Nathke, I. S., J. Heuser, A. Lupas, J. Stock,
C. W. Turck and F. M. Brodsky (1992). Folding
and trimerization of clathrin subunits at the triskelion hub. Cell 68:
899-910.
- Robinson, L. J., S. Pang, D. S. Harris, J. Heuser and
D. E. James (1992). Translocation
of the glucose transporter (GLUT4) to the cell surface in permeabilized 3T3-L1
adipocytes: effects of ATP insulin, and GTP gamma S and localization of GLUT4
to clathrin lattices. J Cell Biol 117: 1181-96.
- Rothberg, K. G., J. E. Heuser, W. C. Donzell,
Y. S. Ying, J. R. Glenney and R. G. Anderson (1992). Caveolin,
a protein component of caveolae membrane coats. Cell 68: 673-82.
- Tardieux, I., P. Webster, J. Ravesloot, W. Boron,
J. A. Lunn, J. E. Heuser and N. W. Andrews (1992). Lysosome
recruitment and fusion are early events required for trypanosome invasion
of mammalian cells. Cell 71: 1117-30.
- Westervelt, P., T. Henkel, D. B. Trowbridge, J.
Orenstein, J. Heuser, H. E. Gendelman and L. Ratner (1992). Dual
regulation of silent and productive infection in monocytes by distinct human
immunodeficiency virus type 1 determinants. J Virol 66: 3925-31.
- Cheney, R. E., M. K. O'Shea, J. E. Heuser,
M. V. Coelho, J. S. Wolenski, E. M. Espreafico, P. Forscher, R. E. Larson
and M. S. Mooseker (1993). Brain
myosin-V is a two-headed unconventional myosin with motor activity. Cell
75: 13-23.
- Heuser, J., Q. Zhu and M. Clarke (1993). Proton
pumps populate the contractile vacuoles of Dictyostelium amoebae. J
Cell Biol 121: 1311-27.
- Jacob-Dubuisson, F., J. Heuser, K. Dodson,
S. Normark and S. Hultgren (1993). Initiation
of assembly and association of the structural elements of a bacterial pilus
depend on two specialized tip proteins. Embo J 12: 837-47.
- Weidman, P., R. Roth and J. Heuser (1993). Golgi
membrane dynamics imaged by freeze-etch electron microscopy: views of different
membrane coatings involved in tubulation versus vesiculation. Cell 75:
123-33.
- Cooper, J. B., J. E. Heuser and J. E. Varner
(1994). 3,4-Dehydroproline
inhibits cell wall assembly and cell division in tobacco protoplasts.
Plant Physiol 104: 747-52.
- Crouch, E., D. Chang, K. Rust, A. Persson and J. Heuser (1994). Recombinant
pulmonary surfactant protein D. Post-translational modification and molecular
assembly. J Biol Chem 269: 15808-13.
- Crouch, E., A. Persson, D. Chang and J. Heuser (1994). Molecular
structure of pulmonary surfactant protein D (SP-D). J Biol Chem 269:
17311-9.
- Prasad, K., J. Heuser, E. Eisenberg and
L. Greene (1994). Complex
formation between clathrin and uncoating ATPase. Journal of Biological
Chemistry 269: 6931-9.
- Schafer, D. A., S. R. Gill, J. A. Cooper, J. E. Heuser and
T. A. Schroer (1994). Ultrastructural
analysis of the dynactin complex: an actin-related protein is a component
of a filament that resembles F-actin. J Cell Biol 126: 403-12.
- Shyng, S. L., J. E. Heuser and D. A. Harris
(1994). A
glycolipid-anchored prion protein is endocytosed via clathrin-coated pits.
J Cell Biol 125: 1239-50.
- Sibley, L. D., J. Dobrowolsky, H. Morisaki and
J. E. Heuser (1994). Invasion and intracellular survival by Toxoplasma
gondii in: D. G. Russell (eds.), Clin. Infect. Dis., Vol. 1: Strategies for
Intracelular Survival of Microbes (pp. 245-264). London: Ballier Tindall Pub.
- Sturgill-Koszycki, S., P. H. Schlesinger, P. Chakraborty,
P. L. Haddix, H. L. Collins, A. K. Fok, R. D. Allen, S. L. Gluck, J. Heuser and
D. G. Russell (1994). Lack
of acidification in Mycobacterium phagosomes produced by exclusion of the
vesicular proton-ATPase. Science 263: 678-81.
- Burns, C. G., M. Reedy, J. Heuser and A.
De Lozanne (1995). Expression
of light meromyosin in Dictyostelium blocks normal myosin II function.
J Cell Biol 130: 605-12.
- Jones, C. H., J. S. Pinkner, R. Roth, J. Heuser,
A. V. Nicholes, S. N. Abraham and S. J. Hultgren (1995). FimH
adhesin of type 1 pili is assembled into a fibrillar tip structure in the
Enterobacteriaceae. Proc Natl Acad Sci U S A 92: 2081-5.
- Morisaki, J. H., J. E. Heuser and L. D.
Sibley (1995). Invasion
of Toxoplasma gondii occurs by active penetration of the host cell. J
Cell Sci 108 ( Pt 6): 2457-64.
- Sapperstein, S. K., D. M. Walter, A. R. Grosvenor,
J. E. Heuser and M. G. Waters (1995). p115
is a general vesicular transport factor related to the yeast endoplasmic reticulum
to Golgi transport factor Uso1p. Proc Natl Acad Sci U S A 92: 522-6.
- Hartshorn, K., D. Chang, K. Rust, M. White, J. Heuser and
E. Crouch (1996). Interactions
of recombinant human pulmonary surfactant protein D and SP-D multimers with
influenza A. Am J Physiol 271: L753-62.
- Lupetti, P., J. E. Heuser, R. Manetti, P.
Massari, S. Lanzavecchia, P. L. Bellon, R. Dallai, R. Rappuoli and J. L. Telford
(1996). Oligomeric
and subunit structure of the Helicobacter pylori vacuolating cytotoxin.
J Cell Biol 133: 801-7.
- Rooney, I. A., J. E. Heuser and J. P. Atkinson
(1996). GPI-anchored
complement regulatory proteins in seminal plasma. An analysis of their physical
condition and the mechanisms of their binding to exogenous cells. J Clin
Invest 97: 1675-86.
- St Geme, J. W., J. S. Pinkner, 3rd, G. P. Krasan,
J. Heuser, E. Bullitt, A. L. Smith and S. J. Hultgren (1996). Haemophilus
influenzae pili are composite structures assembled via the HifB chaperone.
Proc Natl Acad Sci U S A 93: 11913-8.
- Clarke, M. and J. Heuser (1997). Water and
ion transport in: Y. Maeda, K. Inouye and I. Takeuchi (eds.), Dictyostelium:
A Model System for Cell and Developmental Biology (pp. Tokyo: University Academic
Press.
- Cover, T. L., P. I. Hanson and J. E. Heuser (1997). Acid-induced
dissociation of VacA, the Helicobacter pylori vacuolating cytotoxin, reveals
its pattern of assembly. J Cell Biol 138: 759-69.
- Gee, M. A., J. E. Heuser and R. B. Vallee
(1997). An
extended microtubule-binding structure within the dynein motor domain.
Nature 390: 636-9.
- Hanson, P. I., J. E. Heuser and R. Jahn
(1997). Neurotransmitter
release - four years of SNARE complexes. Curr Opin Neurobiol 7: 310-5.
- Hanson, P. I., R. Roth, H. Morisaki, R. Jahn and
J. E. Heuser (1997). Structure
and conformational changes in NSF and its membrane receptor complexes visualized
by quick-freeze/deep-etch electron microscopy. Cell 90: 523-35.
- Lupetti, P., J. E. Heuser, M. Vegni Talluri
and R. Dallai (1997). The gliding movement of gregarines: a high resolution
ultrastructural stud in: A. Delfino (eds.), Recent Advances in Microscopy
of Cells, Tissues, and Organs (pp. Rome.
- Hartman, J. J., J. Mahr, K. McNally, K. Okawa,
A. Iwamatsu, S. Thomas, S. Cheesman, J. Heuser, R. D. Vale and F. J.
McNally (1998). Katanin,
a microtubule-severing protein, is a novel AAA ATPase that targets to the
centrosome using a WD40-containing subunit. Cell 93: 277-87.
- Hsu, S. C., C. D. Hazuka, R. Roth, D. L. Foletti,
J. Heuser and R. H. Scheller (1998). Subunit
composition, protein interactions, and structures of the mammalian brain sec6/8
complex and septin filaments. Neuron 20: 1111-22.
- Katz, L., P. I. Hanson, J. E. Heuser and
P. Brennwald (1998). Genetic
and morphological analyses reveal a critical interaction between the C-termini
of two SNARE proteins and a parallel four helical arrangement for the exocytic
SNARE complex. Embo J 17: 6200-9.
- Lupetti, P., C. Mencarelli, M. Rosetto, J. E. Heuser and
R. Dallai (1998). Structural
and molecular characterization of dynein in a gall-midge insect having motile
sperm with only the outer arm. Cell Motil Cytoskeleton 39: 303-17.
- Mullins, R. D., J. A. Heuser and T. D. Pollard
(1998). The
interaction of Arp2/3 complex with actin: nucleation, high affinity pointed
end capping, and formation of branching networks of filaments. Proc Natl
Acad Sci U S A 95: 6181-6.
- Mulvey, M. A., Y. S. Lopez-Boado, C. L. Wilson,
R. Roth, W. C. Parks, J. Heuser and S. J. Hultgren (1998). Induction
and evasion of host defenses by type 1-piliated uropathogenic Escherichia
coli. Science 282: 1494-7.
- Smith, T. L. (1998). Picture story. A
forceful 'windshield wiper'? Nature Structural Biology 5: 14. [Micrographs
provided by J. Heuser].
- Soto, G. E., K. W. Dodson, D. Ogg, C. Liu, J. Heuser,
S. Knight, J. Kihlberg, C. H. Jones and S. J. Hultgren (1998). Periplasmic
chaperone recognition motif of subunits mediates quaternary interactions in
the pilus. Embo J 17: 6155-67.
- Thanassi, D. G., E. T. Saulino, M. J. Lombardo,
R. Roth, J. Heuser and S. J. Hultgren (1998). The
PapC usher forms an oligomeric channel: implications for pilus biogenesis
across the outer membrane. Proc Natl Acad Sci U S A 95: 3146-51.
- Eckley, D. M., S. R. Gill, K. A. Melkonian, J.
B. Bingham, H. V. Goodson, J. E. Heuser and T. A. Schroer (1999). Analysis
of dynactin subcomplexes reveals a novel actin-related protein associated
with the arp1 minifilament pointed end. J Cell Biol 147: 307-20.
- Graves, M. V., D. E. Burbank, R. Roth, J. Heuser,
P. L. DeAngelis and J. L. Van Etten (1999). Hyaluronan
synthesis in virus PBCV-1-infected chlorella-like green algae. Virology
257: 15-23.
- Hakansson, S., H. Morisaki, J. Heuser and
L. D. Sibley (1999). Time-lapse
video microscopy of gliding motility in Toxoplasma gondii reveals a novel,
biphasic mechanism of cell locomotion. Mol Biol Cell 10: 3539-47.
- Beatty, W. L., E. R. Rhoades, H. J. Ullrich, D.
Chatterjee, J. E. Heuser and D. G. Russell (2000). Trafficking
and release of mycobacterial lipids from infected macrophages. Traffic
1: 235-47.
- Arpinati, M., C. L. Green, S. Heimfeld, J. E. Heuser and
C. Anasetti (2000). Granulocyte-colony
stimulating factor mobilizes T helper 2-inducing dendritic cells. Blood
95: 2484-2490.
- Fujimoto, L. M., R. Roth, J. E. Heuser and
S. L. Schmid (2000). Actin
assembly plays a variable, but not obligatory role in receptor-mediated endocytosis
in mammalian cells. Traffic 1: 161-71.
- Happe, S., M. Cairns, R. Roth, J. Heuser and
P. Weidman (2000). Coatomer
vesicles are not required for inhibition of Golgi transport by G-protein activators.
Traffic 1: 342-53.
- Heuser, J. (2000). The
production of 'cell cortices' for light and electron microscopy. Traffic
1: 545-52.
- Heuser, J. (2000). How
to convert a traditional electron microscopy laboratory to digital imaging:
follow the 'middle road'. Traffic 1: 614-21.
- Heuser, J. E. (2000). Membrane
traffic in anaglyph stereo. Traffic 1: 35-7.
- Moritz, M., M. B. Braunfeld, V. Guenebaut, J. Heuser and
D. A. Agard (2000). Structure
of the gamma-tubulin ring complex: a template for microtubule nucleation.
Nat Cell Biol 2: 365-70.
- Mulvey, M. A., J. D. Schilling, J. J. Martinez
and S. J. Hultgren (2000). Bad
bugs and beleaguered bladders: interplay between uropathogenic Escherichia
coli and innate host defenses. Proceedings of the National Academy of
Sciences of the United States of America 97: 8829-35. [all micrographs provided
by J. Heuser]
- Saber-Lichtenberg, Y., K. Brix, A. Schmitz, J.
E. Heuser, J. H. Wilson, L. Lorand and V. Herzog (2000). Covalent
cross-linking of secreted bovine thyroglobulin by transglutaminase. Faseb
J 14: 1005-14.
- DeMattos, R. B., R. P. Brendza, J. E. Heuser,
M. Kierson, J. R. Cirrito, J. Fryer, P. M. Sullivan, A. M. Fagan, X. Han and
D. M. Holtzman (2001). Purification
and characterization of astrocyte-secreted apolipoprotein E and J-containing
lipoproteins from wild-type and human apoE transgenic mice. Neurochem
Int 39: 415-25.
- Engqvist-Goldstein, A. E., R. A. Warren, M. M.
Kessels, J. H. Keen, J. Heuser and D. G. Drubin (2001). The
actin-binding protein Hip1R associates with clathrin during early stages of
endocytosis and promotes clathrin assembly in vitro. J Cell Biol 154:
1209-23.
- Figueroa-Arredondo, P., J. E. Heuser, N.
S. Akopyants, J. H. Morisaki, S. Giono-Cerezo, F. Enriquez-Rincon and D. E.
Berg (2001). Cell
vacuolation caused by Vibrio cholerae hemolysin. Infect Immun 69: 1613-24.
- Heuser, J. E. and J. G. Donaldson (2001). Membrane-cytoskeletal
dynamics in a new dimension. Nat Cell Biol 3: E140-2.
- Matsuoka, K., R. Schekman, L. Orci and J. E. Heuser (2001). Surface
structure of the COPII-coated vesicle. Proc Natl Acad Sci U S A 98:
13705-9.
- Mencarelli, C., P. Lupetti, M. Rosetto, D. Mercati,
J. E. Heuser and R. Dallai (2001). Molecular
structure of dynein and motility of a giant sperm axoneme provided with only
the outer dynein arm. Cell Motil Cytoskeleton 50: 129-46.
- Raibaud, A., P. Lupetti, R. E. Paul, D. Mercati,
P. T. Brey, R. E. Sinden, J. E. Heuser and R. Dallai (2001). Cryofracture
electron microscopy of the ookinete pellicle of Plasmodium gallinaceum reveals
the existence of novel pores in the alveolar membranes. J Struct Biol
135: 47-57.
- Volkmann, N., K. J. Amann, S. Stoilova-McPhie,
C. Egile, D. C. Winter, L. Hazelwood, J. E. Heuser, R. Li, T. D. Pollard
and D. Hanein (2001). Structure
of Arp2/3 complex in its activated state and in actin filament branch junctions.
Science 293: 2456-9.
- Heuser, J. E. (2001). A critical comparison
between the two current methods of viewing frozen, live cells in the electron
microscope: cryo-electron microscopic tomography versus
"deep-etch" electron microscopy. Biomedical Reviews 12: 11-29.
- Acehan, D., X. Jiang, D. G. Morgan, J. E. Heuser,
X. Wang and C. W. Akey (2002). Three-dimensional
structure of the apoptosome: implications for assembly, procaspase-9 binding,
and activation. Mol Cell 9: 423-32.
- Adrian, M., T. L. Cover, J. Dubochet and J. E. Heuser (2002). Multiple
oligomeric states of the Helicobacter pylori vacuolating toxin demonstrated
by cryo-electron microscopy. J Mol Biol 318: 121-33.
- Chapman, M. R., L. S. Robinson, J. S. Pinkner,
R. Roth, J. Heuser, M. Hammar, S. Normark and S. J. Hultgren (2002). Role
of Escherichia coli curli operons in directing amyloid fiber formation.
Science 295: 851-5.
- Clarke, M., J. Kohler, Q. Arana, T. Liu, J. Heuser and
G. Gerisch (2002). Dynamics
of the vacuolar H(+)-ATPase in the contractile vacuole complex and the endosomal
pathway of Dictyostelium cells. J Cell Sci 115: 2893-905.
- Clarke, M., J. Kohler, J. Heuser and G.
Gerisch (2002). Endosome
fusion and microtubule-based dynamics in the early endocytic pathway of dictyostelium.
Traffic 3: 791-800.
- Davis, E. C., R. A. Roth, J. E. Heuser and
R. P. Mecham (2002). Ultrastructural
properties of ciliary zonule microfibrils. J Struct Biol 139: 65-75.
- Liu, T., C. Mirschberger, L. Chooback, Q. Arana,
Z. Dal Sacco, H. MacWilliams and M. Clarke (2002). Altered
expression of the 100 kDa subunit of the Dictyostelium vacuolar proton pump
impairs enzyme assembly, endocytic function and cytosolic pH regulation.
J Cell Sci 115: 1907-18. [with assistance from J. E. Heuser]
- Ungar, D., T. Oka, E. E. Brittle, E. Vasile, V.
V. Lupashin, J. E. Chatterton, J. E. Heuser, M. Krieger and M. G. Waters
(2002). Characterization
of a mammalian Golgi-localized protein complex, COG, that is required for
normal Golgi morphology and function. J Cell Biol 157: 405-15.
- Weaver, A. M., J. E. Heuser, A. V. Karginov,
W. L. Lee, J. T. Parsons and J. A. Cooper (2002). Interaction
of cortactin and N-WASp with Arp2/3 complex. Curr Biol 12: 1270-8.
- Gerisch, G., J. Heuser and M. Clarke (2002). Tubular-vesicular
transformation in the contractile vacuole system of Dictyostelium. Cell
Biol Int 26: 845-52.
- Fields, S. D., Q. Arana, J. Heuser and M.
Clarke (2002). Mitochondrial
membrane dynamics are altered in cluA- mutants of Dictyostelium. Journal
of Musc Res and Cell Motil 23: 829-38.
- Heuser, J. (2003). Whatever
happened to the 'microtrabecular concept'? Biol Cell 94: 561-96.
- Cao, H., J. D. Orth, J. Chen, S. G. Weller, J.
E. Heuser and M. A. McNiven (2003). Cortactin
is a component of clathrin-coated pits and participates in receptor-mediated
endocytosis. Mol Cell Biol 23: 2162-70.
- Anderson, G. G., J. J. Palermo, J. D. Schilling,
R. Roth, J. Heuser and S. J. Hultgren (2003). Intracellular
bacterial biofilm-like pods in urinary tract infections. Science 301:
105-7.
- Heuser, J. (2003). Pollard/Earnshaw
cell biology. Tissue Cell 35: 153-154.
- Heuser, J. (2003). Retrospective. "My
little spontaneous blips". Science 300: 1248.
- Ritty, T. M., R. Roth and J. E. Heuser (2003). Tendon
cell array isolation reveals a previously unknown fibrillin-2-containing
macromolecular assembly. Structure 11: 1179-1188.
- Tsao, T. S., E. Tomas, H. E. Murrey, C. Hug, D.
H. Lee, N. B. Ruderman, J. E. Heuser and H. F. Lodish (2003). Role
of disulfide bonds in Acrp30/Adiponectin structure and signaling specificity:
Different oligomers activate different signal transduction pathways. J
Biol Chem. 278: 50810-50817.
- Zeng, Y., N. Tao, K. N. Chung, J. E. Heuser and
D. M. Lublin (2003). Endocytosis
of oxidized low density lipoprotein through scavenger receptor CD36 utilizes
a lipid raft pathway that does not require caveolin-1. J Biol Chem 278:
45931-45936.
- Moskowitz, H. S., J. Heuser, T. E. McGraw
and T. A. Ryan (2003). Targeted
chemical disruption of clathrin function in living cells. Mol Biol Cell
14: 4437-4447.
- Stamm, L. M., J. H. Morisaki, L. Y. Gao, R. L.
Jeng, K. L. Mcdonald, R. Roth, S. Takeshita, J. Heuser, M. D. Welch
and E. J. Brown. 2003. Mycobacterium
marinum escapes from phagosomes and is propelled by actin-based motility.
J Exp Med. 198: 1361-1368.
- Balcer, H. I., A. L. Goodman, A. A. Rodal, E. Smith,
J. Kugler, J. E. Heuser and B. L. Goode. 2003. Coordinated
regulation of actin filament turnover by a high-molecular-weight Srv2/CAP
complex, cofilin, profilin, and Aip1. Curr Biol. 13: 2159-2169.
- Bretschneider, T., S. Diez, K. Anderson, J. Heuser,
M. Clarke, A. Muller-Taubenberger, J. Kohler and G. Gerisch (2004). Dynamic
actin patterns and arp2/3 assembly at the substrate-attached surface of motile
cells. Curr Biol 14: 1-10.
- Mishra, S. K., M. J. Hawryluk, T. J. Brett, P.
A. Keyel, A. L. Dupin, A. Jha, J. E. Heuser, D. H. Fremont and L. M.
Traub (2004). Dual-engagement
regulation of protein interactions with the AP-2 adaptor alpha appendage.
J Biol Chem. 279L 46191-46203.
- Naismith, T. V., J. E. Heuser, X. O. Breakefield
and P. I. Hanson (2004). TorsinA
in the nuclear envelope. Proc Natl Acad Sci U S A 101: 7612-7617.
- Sexton, J. A., J. S. Pinkner, R. Roth, J. E. Heuser,
S. J. Hultgren and J. P. Vogel (2004). The
Legionella pneumophila PilT homologue DotB exhibits ATPase activity that is
critical for intracellular growth. J Bacteriol 186: 1658-1666.
- Engqvist-Goldstein, A. E., C. X. Zhang, S. Carreno,
C. Barroso, J. E. Heuser and D. G. Drubin (2004). RNAi-mediated
Hip1R silencing results in stable association between the endocytic machinery
and the actin assembly machinery. Mol Biol Cell 15: 1666-1679.
- Mishra, S. K., M. J. Hawryluk, T. J. Brett, P.
A. Keyel, A. L. Dupin, A. Jha, J. E. Heuser, D. H. Fremont and L. M.
Traub. 2004. Dual
engagement regulation of protein interactions with the AP-2 adaptor alpha
appendage. J Biol Chem. 279: 46191-46203.
- Mccarren, J., J. Heuser, R. Roth, N. Yamada,
M. Martone and B. Brahamsha. 2005. Inactivation
of swmA results in the loss of an outer cell layer in a swimming synechococcus
strain. J Bacteriol. 187: 224-230.
- Quinlan, M. E., J. E. Heuser, E. Kerkhoff
and R. D. Mullins. 2005. Drosophila
Spire is an actin nucleation factor. Nature. 433: 382-388.
- Heuser, J. Deep-etch
EM reveals that the early poxvirus envelope is a single membrane bilayer
stabilized by a geodetic "honeycomb" surface coat. J Cell
Biol. 169: 269-283.
- Szajner, P., A. S. Weisberg, J. Lebowitz, J. Heuser and
B. Moss (2005). External
scaffold of spherical immature poxvirus particles is made of protein trimers,
forming a honeycomb lattice. J Cell Biol 170: 971-981.
- Sahoo, N., W. Beatty, J. Heuser, D. Sept
and L. D. Sibley (2005). Unusual
Kinetic and Structural Properties Control Rapid Assembly and Turnover of Actin
in the Parasite Toxoplasma gondii. Mol Biol Cell. [epub ahead of print]
- Gill, D. B., D. Spitzer, M. Koomey, J. E. Heuser and
J. P. Atkinson (2005). Release
of host-derived membrane vesicles following pilus-mediated adhesion of Neisseria
gonorrhoeae. Cell Microbiol 7: 1672-1683.
- Keyel, P. A., S. K. Mishra, R. Roth, J. E. Heuser,
S. C. Watkins and L. M. Traub (2006). A
single common portal for clathrin-mediated endocytosis of distinct cargo governed
by cargo-selective adaptors. Mol Biol Cell 17: 4300-17.
- Heuser, J. (2006). Evidence
for recycling of contractile vacuole membrane during osmoregulation in Dictyostelium
amoebae--a tribute to Gunther Gerisch. Eur J Cell Biol 85: 859-71.
- Liberton, M., R. Howard Berg, J. Heuser,
R. Roth and H. B. Pakrasi (2006). Ultrastructure
of the membrane systems in the unicellular cyanobacterium Synechocystis sp.
strain PCC 6803. Protoplasma 227: 129-38.
- Buscher, A. Z., S. Grass, J. Heuser, R.
Roth and J. W. St Geme, 3rd (2006). Surface
anchoring of a bacterial adhesin secreted by the two-partner secretion pathway.
Mol Microbiol 61: 470-83.
- Edeling, M. A., S. K. Mishra, P. A. Keyel, A. L.
Steinhauser, B. M. Collins, R. Roth, J. E. Heuser, D. J. Owen and L.
M. Traub (2006). Molecular
switches involving the AP-2 beta2 appendage regulate endocytic cargo selection
and clathrin coat assembly. Dev Cell 10: 329-42.
- Hawryluk, M. J., P. A. Keyel, S. K. Mishra, S.
C. Watkins, J. E. Heuser and L. M. Traub (2006). Epsin
1 is a polyubiquitin-selective clathrin-associated sorting protein. Traffic
7: 262-81.
- Lapaque, N., F. Forquet, C. de Chastellier, Z.
Mishal, G. Jolly, E. Moreno, I. Moriyon, J. E. Heuser, H. T. He and
J. P. Gorvel (2006). Characterization
of Brucella abortus lipopolysaccharide macrodomains as mega rafts. Cell
Microbiol 8: 197-206.
- Sahoo, N., W. Beatty, J. Heuser, D. Sept
and L. D. Sibley (2006). Unusual
kinetic and structural properties control rapid assembly and turnover of actin
in the parasite Toxoplasma gondii. Mol Biol Cell 17: 895-906.
- Keyel, P. A., S. K. Mishra, R. Roth, J. E. Heuser, S. C. Watkins and L.
M. Traub (2006). A
single common portal for clathrin-mediated endocytosis of distinct cargo governed
by cargo-selective adaptors. Mol Biol Cell 17:
4300-17.
- Takamori, S., M. Holt, K. Stenius, E. A. Lemke, M. Gronborg, D. Riedel,
H. Urlaub, S. Schenck, B. Brugger, P. Ringler, S. A. Muller, B. Rammner, F.
Grater, J. S. Hub, B. L. De Groot, G. Mieskes, Y. Moriyama, J. Klingauf, H.
Grubmuller, J. Heuser, F. Wieland and R. Jahn (2006). Molecular
anatomy of a trafficking organelle. Cell 127: 831-46.
- Cardone, G., D. C. Winkler, B. L. Trus, N. Cheng, J. E. Heuser, W. W. Newcomb,
J. C. Brown and A. C. Steven (2007). Visualization
of the herpes simplex virus portal in situ by cryo-electron tomography. Virology 361: 426-34.
- Orlova, A., E. C. Garner, V. E. Galkin, J. Heuser, R. D. Mullins and E.
H. Egelman (2007). The
structure of bacterial ParM filaments. Nat Struct Mol
Biol 14: 921-6.
- Huang, R. H., Y. Wang, R. Roth, X. Yu, A. R. Purvis, J. E. Heuser, E. H.
Egelman and J. E. Sadler (2008). Assembly
of Weibel-Palade body-like tubules from N-terminal domains of von Willebrand
factor. Proc Natl Acad Sci U S A
105: 482-7.
- Hanson, P. I., R. Roth, Y. Lin and J. E. Heuser (2008). Plasma
membrane deformation by circular arrays of ESCRT-III protein filaments. J Cell Biol
180: 389-402.
- Kim, Y., J. E. Heuser, C. M. Waterman and D. W. Cleveland (2008). CENP-E
combines a slow, processive motor and a flexible coiled coil to produce an
essential motile kinetochore tether. J Cell Biol 181: 411-9.
- Galkin,
V. E., X. Yu, J. Bielnicki, J. Heuser, C. P. Ewing, P. Guerry
and E. H. Egelman (2008). Divergence
of quaternary structures among bacterial flagellar filaments. Science 320: 382-385.
- Soman, N. R., G. M. Lanza, J. M. Heuser, P. H. Schlesinger
and S. A. Wickline (2008). Synthesis
and characterization of stable fluorocarbon nanostructures
as drug delivery vehicles for cytolytic peptides. Nano Lett 8: 1131-1136.
- Sheridan,
S. D., X. Yu, R. Roth, J. E. Heuser, M. G. Sehorn, P. Sung,
E. H. Egelman and D. K. Bishop (2008). A
comparative analysis of Dmc1 and Rad51 nucleoprotein filaments. Nucleic Acids
Res 36: 4057-4066.
- Heuser,
J., J. Moller, W. Spendel and G. Pacey (2008). Aqueous
foam drainage characterized by terahertz spectroscopy.
Langmuir 24: 11414-11421.
- Keyel,
P. A., J. R. Thieman, R. Roth, E. Erkan, E. T. Everett,
S. C. Watkins, J. E. Heuser and L. M. Traub (2008). The
AP-2 adaptor beta2 appendage scaffolds alternate cargo
endocytosis. Mol Biol Cell 19: 5309-5326.
- White,
M., P. Kingma, T. Tecle, N. Kacak, B. Linders, J. Heuser,
E. Crouch and K. Hartshorn (2008). Multimerization
of surfactant protein D, but not its collagen domain, is
required for antiviral and opsonic activities related to
influenza virus. J Immunol 181: 7936-7943.
- Huang, J., R. Roth, J. E. Heuser and J. E. Sadler (2009). Integrin
alpha(v)beta(3) on human endothelial cells binds von Willebrand
factor strings under fluid shear stress. Blood 113:
1589-1597.
- Ren, P. H., J. E. Lauckner, I. Kachirskaia, J. E. Heuser,
R. Melki and R. R. Kopito (2009). Cytoplasmic
penetration and persistent infection of mammalian cells by
polyglutamine aggregates. Nat Cell Biol 11: 219-225.
- Pei-Hsien Ren, Ioulia Kachirskaia,
John Heuser, and Ron Kopito (2008). Cytoplasmic penetration
and prion-like propagation of extracellular polyglutamine
aggregates in mammalian cells. Nature Cell Biol. (in press).
|